domingo, 28 de septiembre de 2008

Nationwide outbreak of Salmonella enterica serotype Give infections in infants in France, linked to infant milk formula

Contaminated infant milk formula seems to be the source.

An outbreak of Salmonella enterica serotype Give was informed in the hospital of Nantes in west France in an exclusively bottle-fed infant. On Monday morning 22 September, two additional cases of salmonellosis in infants were reported by the hospital of Niort in southwest France. The serotype of the three cases was unknown at that time.

At the same time, the database of the French national reference centre (NRC) for Salmonella showed a recent increase in the proportion of Salmonella enterica serotype Give isolates from infants. The overall number of S. Give isolates received by the NRC in 2008 was 19, similar compared to the same period in previous years. However, six of the recent isolates had been obtained from infants, whereas this proportion was zero in previous years.

Epidemiological investigations: An investigation was started to identify any common exposures between the three reported cases of infant salmonellosis, and to identify the serotype(s) involved. In addition, we investigated the cases of S. Give in infants identified by the NRC.

The parents of the three reported infant Salmonella enterica cases were interviewed by the district health office on their consumption of foods and drink and other exposures. The infants, aged 9 weeks, and 4 and 5 months respectively, had developed symptoms of febrile diarrhoea between 13 and 18 September and had been hospitalised between 17 and 19 September. The infants had not been in contact with other diarrhoea cases, and had no common exposures except for their infant formula milk. All three drank the same brand (brand X) formula milk. The batch number of the product consumed during the days before the onset of symptoms was known for two cases. The serotype of one of the three isolates was known on 25 September and confirmed as Give.


Aporte: Guillermo Figueroa

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